close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DLG5Disks large homolog 5 isoform X1. (2026 aa)    
Predicted Functional Partners:
CASK
Calcium/calmodulin-dependent serine protein kinase.
    
0.786
ITSN2
Intersectin-2 isoform X1.
   
 0.638
GRIN1
Glutamate receptor ionotropic, NMDA 1 isoform X1.
   
 0.635
EFCAB7
EF-hand calcium-binding domain-containing protein 7.
    
 0.625
RND2
Rho-related GTP-binding protein RhoN.
    
  0.604
EVC2
Ellis van creveld syndrome protein 2.
      
 0.599
RHOU
Rho-related GTP-binding protein RhoU.
    
  0.567
RND1
Rho-related GTP-binding protein Rho6.
    
  0.567
RHOV
Rho-related GTP-binding protein RhoV.
    
  0.567
RND3
Rho-related GTP-binding protein RhoE.
    
  0.567
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.