close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1. (1327 aa)    
Predicted Functional Partners:
PDGFRB
Platelet-derived growth factor receptor beta.
    
 0.982
PDGFRA
Platelet-derived growth factor receptor alpha.
    
 0.955
ERBB4
Receptor tyrosine-protein kinase erbB-4 isoform X1.
    
 0.954
ERBB2
Receptor tyrosine-protein kinase erbB-2.
    
 0.954
EGFR
Epidermal growth factor receptor isoform X1.
    
 0.954
KDR
Vascular endothelial growth factor receptor 2.
    
 0.944
ITPR1
Inositol 1,4,5-trisphosphate receptor type 1 isoform X1.
     
 0.921
ITPR2
Inositol 1,4,5-trisphosphate receptor type 2 isoform X1.
     
 0.921
ITPKB
1D-myo-inositol-triphosphate 3-kinase.
     
 0.921
ITPKA
Inositol-trisphosphate 3-kinase A isoform X1.
     
 0.921
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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