close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LYSTLysosomal-trafficking regulator. (3804 aa)    
Predicted Functional Partners:
FIG4
Phosphatidylinositol 3,5-bisphosphate 5-phosphatase.
   
  
 0.692
ESR1
Estrogen receptor isoform X1.
      
 0.690
VTA1
Vacuolar protein sorting-associated protein VTA1 homolog isoform X2.
    
 
 0.564
SMPD2
Sphingomyelin phosphodiesterase 2 isoform X1.
     
 0.507
SQSTM1
Sequestosome-1 isoform X1.
   
 
 0.503
RACK1
Guanine nucleotide-binding protein subunit beta-2-like 1 protein.
    
 0.493
MMUT
Methylmalonyl-CoA mutase, mitochondrial isoform X1.
      
 0.469
STX11
Syntaxin 11.
      
 0.468
NOLC1
Nucleolar and coiled-body phosphoprotein 1 isoform X1.
      
 0.450
TNFSF15
TNF superfamily member 15.
   
 
 0.431
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.