close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STK4Serine/threonine-protein kinase 4 isoform X1. (504 aa)    
Predicted Functional Partners:
CASP3
Caspase 3.
   
 0.957
SAV1
Protein salvador homolog 1.
    
 0.956
LOC107199276
MOB kinase activator 1A.
   
 0.932
FOXO1
Forkhead box protein O1.
    
 0.914
FOXO3
Forkhead box protein O3.
    
 0.914
FOXO6
Forkhead box protein O6.
    
 0.913
FOXO4
Forkhead box protein O4.
    
 0.913
STK3
Serine/threonine-protein kinase 3 isoform X1.
  
  
 
0.901
WWTR1
WW domain-containing transcription regulator protein 1 isoform X1.
    
 0.812
YAP1
Transcriptional coactivator YAP1 isoform X1.
    
 0.812
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.