Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WNK2Serine/threonine-protein kinase WNK2 isoform X3. (2297 aa)    
Predicted Functional Partners:
GAK
Cyclin-G-associated kinase isoform X1.
    
 0.467
TRAF7
E3 ubiquitin-protein ligase TRAF7 isoform X1.
   
 0.455
MIB2
E3 ubiquitin-protein ligase MIB2 isoform X1.
    
 0.432
ENSPMJP00000025069
annotation not available
   
 0.424
PELI1
E3 ubiquitin-protein ligase pellino homolog 1.
    
 0.420
PELI2
E3 ubiquitin-protein ligase pellino homolog 2 isoform X1.
    
 0.420
UBE2V1
Ubiquitin-conjugating enzyme E2 variant 1.
    
 0.413
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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