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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDX58Probable ATP-dependent RNA helicase DDX58 isoform X1. (1026 aa)    
Predicted Functional Partners:
DHX58
Probable ATP-dependent RNA helicase DHX58.
   
0.983
ATG12
Ubiquitin-like protein ATG12.
    
 0.971
CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD isoform X1.
    
 0.946
OASL
2'-5'-oligoadenylate synthase-like protein.
   
 0.935
PANK2
Mitochondrial antiviral-signaling protein.
     
  0.900
RPS27A
Ubiquitin-small subunit ribosomal protein S27Ae.
   
 0.894
EIF2AK2
Interferon-induced, double-stranded RNA-activated protein kinase isoform X1.
   
 0.885
USP18
Ubl carboxyl-terminal hydrolase 18 isoform X1.
   
 
 0.838
IFIH1
Interferon-induced helicase C domain-containing protein 1 isoform X1.
   
 
0.786
UBA52
Ubiquitin-large subunit ribosomal protein L40e.
    
  0.785
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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