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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPDYASpeedy protein A. (308 aa)    
Predicted Functional Partners:
CDK1
Cyclin-dependent kinase 1.
   
 0.940
NFYB
Nuclear transcription factor Y subunit beta.
   
 0.859
NFYA
Nuclear transcription factor Y subunit alpha isoform X1.
    
 0.856
CDK3
Cyclin-dependent kinase 3.
   
 0.842
POLE3
DNA polymerase epsilon subunit 3.
    
 0.826
SUN1
SUN domain-containing protein 1 isoform X1.
    
 
 0.766
CDKN1B
Cyclin-dependent kinase inhibitor 1B.
    
 
 0.536
CDKN1A
Cyclin-dependent kinase inhibitor 1A.
    
 
 0.536
SUN2
SUN domain-containing protein 2 isoform X1.
    
 
 0.450
POLE
DNA polymerase epsilon catalytic subunit A.
    
 0.422
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.