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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MARCHF2E3 ubiquitin-protein ligase MARCH2 isoform X1. (323 aa)    
Predicted Functional Partners:
CNOT2
CCR4-NOT transcription complex subunit 2.
    
 
 0.557
FAF1
FAS-associated factor 1.
    
 
 0.423
FAF2
FAS-associated factor 2 isoform X1.
    
 
 0.423
UBE2G2
Ubiquitin conjugating enzyme E2 G2.
    
 
 0.420
VCP
Transitional endoplasmic reticulum ATPase isoform X1.
    
 
 0.401
SPATA5
Spermatogenesis-associated protein 5 isoform X1.
    
 
 0.401
SPATA5L1
Spermatogenesis-associated protein 5-like protein 1.
    
 
 0.401
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.