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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TEFThyrotroph embryonic factor isoform X1. (318 aa)    
Predicted Functional Partners:
NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating.
   
 
 0.687
COX5A
Cytochrome c oxidase subunit 5A, mitochondrial.
   
 0.621
COX2
Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.
    
 0.602
COX7C
Cytochrome c oxidase subunit 7C, mitochondrial.
   
 0.569
C1orf198
Uncharacterized protein C1orf198 homolog.
   
 0.562
COX5B
Cytochrome c oxidase subunit 5B, mitochondrial.
   
 0.562
COA6
Cytochrome c oxidase assembly factor 6 homolog.
   
 0.559
NR1D2
LOW QUALITY PROTEIN: nuclear receptor subfamily 1 group D member 2.
   
 0.555
COX4I1
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial isoform X1.
   
 0.549
ATF4
Cyclic AMP-dependent transcription factor ATF-4.
   
 0.524
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.