Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SH2B3SH2B adaptor protein 1/3. (574 aa)    
Predicted Functional Partners:
LOC107199430
Tyrosine-protein kinase JAK3-like.
    
 0.797
JAK2
Tyrosine-protein kinase JAK2 isoform X1.
    
 0.797
JAK1
Tyrosine-protein kinase JAK1.
    
 0.701
SHROOM3
Protein Shroom3 isoform X1.
      
 0.681
KIT
Mast/stem cell growth factor receptor Kit isoform X1.
    
 0.670
CASZ1
Zinc finger protein castor homolog 1 isoform X2.
      
 0.629
FLT3
Receptor-type tyrosine-protein kinase FLT3 isoform X1.
    
 0.553
CBL
E3 ubiquitin-protein ligase CBL isoform X1.
    
 0.551
CBLB
E3 ubiquitin-protein ligase CBL-B isoform X1.
    
 0.551
PPM1F
Protein phosphatase 1F isoform X1.
      
 0.550
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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