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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH2B3SH2B adaptor protein 1/3. (574 aa)    
Predicted Functional Partners:
LOC107199430
Tyrosine-protein kinase JAK3-like.
    
 0.671
JAK2
Tyrosine-protein kinase JAK2 isoform X1.
    
 0.671
KITLG
Kit ligand isoform X1.
     
 0.620
KIT
Mast/stem cell growth factor receptor Kit isoform X1.
    
 0.572
JAK1
Tyrosine-protein kinase JAK1.
    
 0.560
CBL
E3 ubiquitin-protein ligase CBL isoform X1.
    
 0.519
CBLB
E3 ubiquitin-protein ligase CBL-B isoform X1.
    
 0.519
CSF1R
Macrophage colony-stimulating factor 1 receptor.
    
 0.513
CCDC92
Coiled-coil domain-containing protein 92.
      
 0.505
GRB2
Growth factor receptor-binding protein 2.
    
0.495
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.