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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OGG18-oxoguanine DNA glycosylase. (361 aa)    
Predicted Functional Partners:
APEX1
DNA-(apurinic or apyrimidinic site) lyase.
  
 0.905
NEIL1
Nei like DNA glycosylase 1.
     
 0.841
NT5E
5'-nucleotidase.
   
 
  0.837
POLH
DNA polymerase eta.
  
 
 0.793
MGMT
Methylated-DNA--protein-cysteine methyltransferase isoform X1.
  
  
 0.772
MSH6
DNA mismatch repair protein MSH6.
   
 
 0.762
NEIL2
Endonuclease VIII-like 2.
     
 0.744
NTHL1
Endonuclease III-like protein 1 isoform X1.
   
 
 0.728
WRN
Werner syndrome ATP-dependent helicase isoform X1.
    
 
 0.724
FEN1
Flap endonuclease 1.
   
 
 0.715
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.