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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STN1CST complex subunit STN1 isoform X1. (368 aa)    
Predicted Functional Partners:
WRN
Werner syndrome ATP-dependent helicase isoform X1.
   
 0.992
TEN1
CST complex subunit TEN1 isoform X1.
    
 0.988
CTC1
CST complex subunit CTC1 isoform X1.
    
 0.985
POLA1
DNA polymerase alpha catalytic subunit isoform X1.
   
 0.958
PRIM2
DNA primase large subunit.
   
 0.953
PRIM1
DNA primase subunit 1.
   
 0.949
RPA3
Replication protein A 14 kDa subunit.
   
 0.941
ENSPMJP00000018528
annotation not available
   
 0.933
FANCM
Fanconi anemia group M protein.
   
 0.933
MED27
Mediator of RNA polymerase II transcription subunit 27 isoform X1.
   
  0.918
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.