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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIPAH receptor-interacting protein isoform X1. (482 aa)    
Predicted Functional Partners:
HSP90AB1
LOW QUALITY PROTEIN: heat shock protein HSP 90-beta.
    
 0.817
HSP90AA1
Heat shock protein HSP 90-alpha.
    
 0.817
PTGES3
Prostaglandin E synthase 3.
    
 0.807
LOC107207636
Aryl hydrocarbon receptor-like.
    
 0.733
ENSPMJP00000007662
annotation not available
    
 0.733
AHR
Aryl hydrocarbon receptor.
    
 0.733
PTGES3L
Putative protein PTGES3L.
    
 0.721
AHRR
Aryl hydrocarbon receptor repressor.
    
 0.700
TSC1
Tuberous sclerosis 1.
    
 0.695
TRAP1
Heat shock protein 75 kDa, mitochondrial.
    
 0.695
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.