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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRAIPE3 ubiquitin-protein ligase TRAIP isoform X1. (491 aa)    
Predicted Functional Partners:
LRR1
Leucine-rich repeat protein 1.
   
  
 0.666
NEIL3
Endonuclease 8-like 3 isoform X1.
   
  
 0.585
FANCD2
Fanconi anemia group D2 protein.
   
 
 0.559
TATDN3
Putative deoxyribonuclease TATDN3 isoform X1.
      
 0.533
FBXO5
F-box only protein 5 isoform X1.
   
  
 0.532
USP37
Ubiquitin carboxyl-terminal hydrolase 26/29/37.
    
 
 0.526
SPRTN
SprT-like domain-containing protein Spartan.
      
 0.520
CDC45
Cell division control protein 45 homolog.
   
  
 0.467
UFD1
Ubiquitin fusion degradation protein 1 homolog isoform X1.
      
 0.463
NSMCE2
E3 SUMO-protein ligase NSE2 isoform X1.
      
 0.449
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.