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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHOC2Leucine-rich repeat protein SHOC-2. (582 aa)    
Predicted Functional Partners:
MRAS
Ras-related protein M-Ras.
    
 0.973
PPP1CC
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit.
    
 0.866
PPP1CA
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit.
    
 0.866
PPP1CB
Protein phosphatase 1 catalytic subunit beta.
   
 0.851
PIAS2
E3 SUMO-protein ligase PIAS2 isoform X5.
   
  
 0.691
ADGRL3
Adhesion G protein-coupled receptor L3 isoform X1.
    
 
 0.641
ADGRL2
Adhesion G protein-coupled receptor L2 isoform X1.
    
 
 0.641
BRAF
B-Raf proto-oncogene serine/threonine-protein kinase.
    
 0.639
ENSPMJP00000002805
Adhesion G protein-coupled receptor L2.
    
 
 0.637
REM1
GTP-binding protein REM 1.
    
 0.604
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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