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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KMT2DLOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2D. (407 aa)    
Predicted Functional Partners:
ENSPMJP00000006170
annotation not available
 
      0.899
ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2 isoform X1.
    
 0.886
RBBP5
Retinoblastoma-binding protein 5.
    
 0.878
WDR5B
WD repeat-containing protein 5.
   
 0.744
ENSPMJP00000002721
annotation not available
    
 0.718
KDM6A
Lysine-specific demethylase 6A isoform X1.
   
 0.668
CAMKMT
Calmodulin-lysine N-methyltransferase isoform X1.
     
 0.659
PRKAB1
5'-AMP-activated protein kinase subunit beta-1 isoform X1.
    
  0.658
PRKAA1
5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X1.
   
  0.654
EP300
Histone acetyltransferase p300 isoform X1.
   
 0.653
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.