TCF7L2 protein (Parus major) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

TCF7L2

Transcription factor 7-like 2 isoform X1. (486 aa)

Predicted Functional Partners:

CTNNB1

0.994

NLK

0.982

LEF1

0.960

CREBBP

0.953

EP300

0.952

CTBP2

0.947

LOC107210813

0.947

CTBP1

0.947

SOX17

0.942

RUVBL1

0.940

Your Current Organism:

Parus major

NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CREBBP	CTBP1	ENSPMJP00000013200	ENSPMJP00000022674	CREB-binding protein isoform X1.	C-terminal-binding protein 1 isoform X1.	0.402
CREBBP	CTBP2	ENSPMJP00000013200	ENSPMJP00000007069	CREB-binding protein isoform X1.	C-terminal-binding protein 2 isoform X1.	0.402
CREBBP	CTNNB1	ENSPMJP00000013200	ENSPMJP00000014037	CREB-binding protein isoform X1.	Catenin beta-1 isoform X1.	0.968
CREBBP	EP300	ENSPMJP00000013200	ENSPMJP00000009266	CREB-binding protein isoform X1.	Histone acetyltransferase p300 isoform X1.	0.997
CREBBP	LEF1	ENSPMJP00000013200	ENSPMJP00000013194	CREB-binding protein isoform X1.	Lymphoid enhancer-binding factor 1 isoform X1.	0.970
CREBBP	RUVBL1	ENSPMJP00000013200	ENSPMJP00000016994	CREB-binding protein isoform X1.	RuvB-like protein 1 (pontin 52).	0.511
CREBBP	TCF7L2	ENSPMJP00000013200	ENSPMJP00000006238	CREB-binding protein isoform X1.	Transcription factor 7-like 2 isoform X1.	0.953
CTBP1	CREBBP	ENSPMJP00000022674	ENSPMJP00000013200	C-terminal-binding protein 1 isoform X1.	CREB-binding protein isoform X1.	0.402
CTBP1	CTBP2	ENSPMJP00000022674	ENSPMJP00000007069	C-terminal-binding protein 1 isoform X1.	C-terminal-binding protein 2 isoform X1.	0.901
CTBP1	CTNNB1	ENSPMJP00000022674	ENSPMJP00000014037	C-terminal-binding protein 1 isoform X1.	Catenin beta-1 isoform X1.	0.688
CTBP1	EP300	ENSPMJP00000022674	ENSPMJP00000009266	C-terminal-binding protein 1 isoform X1.	Histone acetyltransferase p300 isoform X1.	0.407
CTBP1	LEF1	ENSPMJP00000022674	ENSPMJP00000013194	C-terminal-binding protein 1 isoform X1.	Lymphoid enhancer-binding factor 1 isoform X1.	0.948
CTBP1	LOC107210813	ENSPMJP00000022674	ENSPMJP00000007368	C-terminal-binding protein 1 isoform X1.	C-terminal-binding protein 2.	0.911
CTBP1	TCF7L2	ENSPMJP00000022674	ENSPMJP00000006238	C-terminal-binding protein 1 isoform X1.	Transcription factor 7-like 2 isoform X1.	0.947
CTBP2	CREBBP	ENSPMJP00000007069	ENSPMJP00000013200	C-terminal-binding protein 2 isoform X1.	CREB-binding protein isoform X1.	0.402
CTBP2	CTBP1	ENSPMJP00000007069	ENSPMJP00000022674	C-terminal-binding protein 2 isoform X1.	C-terminal-binding protein 1 isoform X1.	0.901
CTBP2	CTNNB1	ENSPMJP00000007069	ENSPMJP00000014037	C-terminal-binding protein 2 isoform X1.	Catenin beta-1 isoform X1.	0.688
CTBP2	EP300	ENSPMJP00000007069	ENSPMJP00000009266	C-terminal-binding protein 2 isoform X1.	Histone acetyltransferase p300 isoform X1.	0.407
CTBP2	LEF1	ENSPMJP00000007069	ENSPMJP00000013194	C-terminal-binding protein 2 isoform X1.	Lymphoid enhancer-binding factor 1 isoform X1.	0.948
CTBP2	LOC107210813	ENSPMJP00000007069	ENSPMJP00000007368	C-terminal-binding protein 2 isoform X1.	C-terminal-binding protein 2.	0.911