Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HNF4GHepatocyte nuclear factor 4-gamma isoform X1. (454 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta-1 isoform X1.
    
 
 0.806
PPARGC1A
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1.
    
 
 0.774
NR0B2
Nuclear receptor subfamily 0 group B member 2 isoform X1.
   
 0.761
CREBBP
CREB-binding protein isoform X1.
    
 
 0.718
HNF1A
HNF1 homeobox A.
   
 0.664
MED1
Mediator of RNA polymerase II transcription subunit 1.
    
  0.617
LOC107200218
Mediator of RNA polymerase II transcription subunit 1-like.
    
  0.617
SP1
Sp1 transcription factor.
    
 
 0.594
HNF1B
Transcription factor 2, hepatocyte nuclear factor 1-beta.
   
 0.578
VSX2
Visual system homeobox 2.
      
 0.536
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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