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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHMP4CCharged multivesicular body protein 4c. (220 aa)    
Predicted Functional Partners:
CHMP5
Charged multivesicular body protein 5.
  
0.994
CHMP6
Charged multivesicular body protein 6.
    
0.994
VPS4B
Vacuolar protein sorting-associated protein 4B.
    
 0.991
VPS4A
Vacuolar protein sorting-associated protein 4A.
    
 0.991
PDCD6IP
Programmed cell death 6-interacting protein isoform X1.
   
 0.990
CHMP7
Charged multivesicular body protein 7 isoform X1.
    
0.983
CHMP2B
Charged multivesicular body protein 2B.
    
 0.981
CHMP1B
Charged multivesicular body protein 1b.
    
 0.973
CHMP1A
Charged multivesicular body protein 1a.
    
 0.973
LOC107202897
Charged multivesicular body protein 3.
   
 0.964
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.