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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RGS10Regulator of G-protein signaling 10 isoform X1. (181 aa)    
Predicted Functional Partners:
GNB5
Guanine nucleotide-binding protein subunit beta-5.
   
 0.687
APC
Adenomatous polyposis coli protein isoform X1.
    
 0.596
GNAO1
Guanine nucleotide-binding protein G(o) subunit alpha isoform X1.
   
 0.511
GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1.
   
 0.511
GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha.
   
 0.511
GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2.
   
 0.511
GNA13
Guanine nucleotide-binding protein subunit alpha-13.
   
 0.504
SUCLG2
succinate-CoA ligase GDP-forming beta subunit.
      
 0.465
CSNK1A1
Casein kinase I isoform X1.
    
 0.455
OGFR
Opioid growth factor receptor isoform X1.
    
 0.455
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.