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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ILKIntegrin-linked protein kinase. (452 aa)    
Predicted Functional Partners:
PARVA
Alpha-parvin.
   
 0.995
PARVB
Beta-parvin.
   
 0.995
PARVG
Gamma-parvin isoform X1.
   
 0.994
LIMS1
LIM and senescent cell antigen-like-containing domain protein 1 isoform X1.
   
 0.963
LIMS2
LIM and senescent cell antigen-like-containing domain protein 1/2.
   
 0.963
AKT1
RAC-alpha serine/threonine-protein kinase.
   
 0.949
AKT3
RAC-gamma serine/threonine-protein kinase isoform X1.
   
 0.949
RSU1
Ras suppressor protein 1.
   
 0.942
PIK3R2
Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.
    
 0.905
PIK3R1
Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.
    
 0.905
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.