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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARD3Partitioning defective 3 homolog isoform X2. (1345 aa)    
Predicted Functional Partners:
PRKCI
Protein kinase C iota type isoform X1.
    
 0.989
PRKCZ
Protein kinase C zeta type isoform X1.
    
 0.989
PARD6A
Partitioning defective 6 homolog alpha isoform X1.
    
 0.950
NECTIN1
Poliovirus receptor-related protein 1.
    
 0.939
JAM3
Junctional adhesion molecule 3.
    
 0.934
TIAM1
T-lymphoma invasion and metastasis-inducing protein 1 isoform X1.
    
 0.929
NECTIN3
Poliovirus receptor-related protein 3.
   
 0.913
JAM2
Junctional adhesion molecule B isoform X1.
    
 0.913
CLDN14
Claudin-14.
     
 0.905
ENSPMJP00000002373
Claudin-22-like.
   
  0.904
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.