Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDH17Cadherin 17, LI cadherin. (833 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta-1 isoform X1.
    
 0.948
PRKAA1
5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X1.
      
 0.911
CLDN12
Claudin-12.
      
 0.789
TIMP2
LOW QUALITY PROTEIN: metalloproteinase inhibitor 2.
   
  
 0.774
JUP
Junction plakoglobin.
    
 0.738
MDM2
E3 ubiquitin-protein ligase Mdm2 isoform X1.
    
 0.703
ATM
Serine-protein kinase ATM isoform X1.
      
 0.696
CYP2R1
Vitamin D 25-hydroxylase.
   
  
 0.694
CTNND1
Catenin (cadherin-associated protein), delta 1.
    
 0.685
ARVCF
Armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X1.
    
 0.685
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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