Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MGMTMethylated-DNA--protein-cysteine methyltransferase isoform X1. (202 aa)    
Predicted Functional Partners:
TRIP12
E3 ubiquitin-protein ligase TRIP12 isoform X1.
    
 
 0.876
IDH1
Isocitrate dehydrogenase [NADP] cytoplasmic.
     
 0.784
IDH2
Isocitrate dehydrogenase [NADP], mitochondrial.
     
 0.707
DHDDS
Dehydrodolichyl diphosphate synthase complex subunit DHDDS.
      
 0.701
PCNA
Proliferating cell nuclear antigen.
   
 
 0.676
MLH1
DNA mismatch repair protein MLH1.
   
 
 0.576
MSH6
DNA mismatch repair protein MSH6.
   
 
 0.572
OGG1
8-oxoguanine DNA glycosylase.
  
  
 0.554
ATRX
Transcriptional regulator ATRX isoform X1.
      
 0.549
PMS2
Mismatch repair endonuclease PMS2.
   
 
 0.543
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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