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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAD2L2Mitotic spindle assembly checkpoint protein MAD2B. (217 aa)    
Predicted Functional Partners:
REV3L
DNA polymerase zeta catalytic subunit.
    
 0.998
REV1
DNA repair protein REV1 isoform X1.
   
 0.997
MAD2L1
Mitotic spindle assembly checkpoint protein MAD2A.
    
0.969
POLD2
DNA polymerase delta 2, accessory subunit.
    
 
 0.960
POLD3
DNA polymerase delta subunit 3 isoform X1.
    
 
 0.958
SHLD2
Protein FAM35A isoform X1.
    
 
 0.954
POLH
DNA polymerase eta.
   
 0.951
FZR1
Cell division cycle 20-like protein 1, cofactor of APC complex.
   
 0.937
BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1 isoform X1.
     
 0.924
POLE
DNA polymerase epsilon catalytic subunit A.
    
 0.917
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.