Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LCKLymphocyte cell-specific protein tyrosine kinase. (508 aa)    
Predicted Functional Partners:
CD4
T-cell surface glycoprotein CD4 isoform X1.
   
 0.954
ZAP70
Tyrosine-protein kinase ZAP-70.
   
 0.923
CD247
LOW QUALITY PROTEIN: T-cell surface glycoprotein CD3 zeta chain.
   
 0.920
LYN
Tyrosine-protein kinase Lyn isoform X1.
   
 0.885
SYK
Tyrosine-protein kinase SYK.
   
 0.879
PTPRC
Receptor-type tyrosine-protein phosphatase C isoform X1.
   
 0.867
ENSPMJP00000024181
Docking protein 2-like.
   
 0.848
PTPN6
Tyrosine-protein phosphatase non-receptor type 6 isoform X1.
   
 0.823
CD8A
T-cell surface glycoprotein CD8 alpha chain isoform X1.
   
 
 0.812
PTK2
Focal adhesion kinase 1 isoform X1.
   
 0.805
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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