Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WEE1Wee1-like protein kinase isoform X1. (643 aa)    
Predicted Functional Partners:
CDK1
Cyclin-dependent kinase 1.
   
0.995
WEE2
Wee1-like protein kinase 2 isoform X1.
  
  
 
0.902
CDC25A
M-phase inducer phosphatase 1 isoform X1.
   
 0.897
CCNB2
G2/mitotic-specific cyclin-B2.
   
 0.888
CCNA1
Cyclin-A1.
   
 0.884
CHEK1
Serine/threonine-protein kinase Chk1 isoform X1.
   
 0.862
CCNA2
Cyclin-A2 isoform X1.
   
 0.855
PLK1
Serine/threonine-protein kinase PLK1.
   
 0.852
CDK3
Cyclin-dependent kinase 3.
   
 0.851
PLK2
Serine/threonine-protein kinase PLK2.
   
 0.794
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.