Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
DENND2BSuppression of tumorigenicity 5 protein isoform X1. (1118 aa)    
Predicted Functional Partners:
ITSN2
Intersectin-2 isoform X1.
    
 
 0.566
RAB9A
Ras-related protein Rab-9A isoform X1.
     
 0.547
RHOBTB3
Rho-related BTB domain-containing protein 3-like.
      
 0.541
IFT27
Intraflagellar transport protein 27 homolog.
    
 0.516
RAB35
Ras-related protein Rab-35.
    
 0.516
SUOX
Sulfite oxidase, mitochondrial.
      
 0.446
AVL9
Late secretory pathway protein AVL9 homolog.
      
 0.442
RIC3
Protein RIC-3 isoform X1.
      
 0.440
NUCB2
Nucleobindin-2.
      
 0.437
GALNT12
Polypeptide N-acetylgalactosaminyltransferase 12 isoform X1.
      
 0.434
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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