close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NDFIP1NEDD4 family-interacting protein 1. (246 aa)    
Predicted Functional Partners:
TRIP12
E3 ubiquitin-protein ligase TRIP12 isoform X1.
      
 0.689
WWP2
WW domain containing E3 ubiquitin protein ligase 2.
    
 
 0.663
WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1.
    
 
 0.659
ATP6AP1
V-type H+-transporting ATPase S1 subunit.
   
  
 0.557
NDUFA6
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6.
      
 0.547
NEDD4L
E3 ubiquitin-protein ligase NEDD4-like isoform X1.
    
 
 0.526
NEDD4
E3 ubiquitin-protein ligase NEDD4 isoform X1.
    
 
 0.526
ITCH
E3 ubiquitin-protein ligase Itchy homolog isoform X1.
    
 
 0.470
SMURF2
E3 ubiquitin-protein ligase SMURF2.
    
 
 0.465
LOC107199188
Natural resistance-associated macrophage protein 2-like.
   
 
 0.457
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.