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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPMJP00000007706annotation not available (65 aa)    
Predicted Functional Partners:
JAK1
Tyrosine-protein kinase JAK1.
   
 0.897
LOC107198545
Interferon alpha/beta receptor 2-like isoform X1.
   
 0.894
ENSPMJP00000000328
annotation not available
   
 0.735
IL10RA
Interleukin-10 receptor subunit alpha.
   
 0.683
ENSPMJP00000002265
Signal transducer and activator of transcription 2.
   
 0.681
STAT1
Signal transducer and activator of transcription 1-alpha/beta isoform X1.
   
 0.677
ENSPMJP00000000338
annotation not available
    
 0.654
STAT3
Signal transducer and activator of transcription 3 isoform X1.
   
 0.626
IL10
Interleukin 10.
    
 0.622
LOC107199430
Tyrosine-protein kinase JAK3-like.
   
 0.599
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.