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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C2H5orf49Uncharacterized protein C5orf49 homolog. (146 aa)    
Predicted Functional Partners:
C9orf116
Chromosome 9 open reading frame 116.
    
 
 0.829
CFAP161
Cilia- and flagella-associated protein 161.
   
 
 0.605
ENKUR
Enkurin isoform X1.
    
 
 0.597
NME7
Nucleoside diphosphate kinase 7.
    
 
 0.583
ARMC3
Armadillo repeat containing 3.
   
  
 0.579
EFCAB1
EF-hand calcium-binding domain-containing protein 1 isoform X1.
    
 
 0.565
IFT57
Intraflagellar transport protein 57 homolog.
      
 0.565
CFAP77
Cilia- and flagella-associated protein 77.
   
   0.535
CCDC170
Coiled-coil domain-containing protein 170 isoform X1.
      
 0.533
TEKT1
Tektin-1.
   
   0.532
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.