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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACVRL1Serine/threonine-protein kinase receptor R3. (578 aa)    
Predicted Functional Partners:
BMP10
Bone morphogenetic protein 10.
    
 0.985
GDF2
Growth differentiation factor 2.
    
 0.985
BMPR2
Bone morphogenetic protein receptor type-2.
   
0.971
TGFB3
Transforming growth factor beta-3.
    
 0.954
TGFBR2
TGF-beta receptor type-2.
   
0.949
ACVR2A
Activin receptor type-2A isoform X1.
  
0.944
LOC107207553
TGF-beta receptor type-2-like.
   
0.916
ENG
Endoglin isoform X1.
   
 
 0.825
TGFB1
Transforming growth factor beta-1 isoform X1.
    
 0.757
ACVR2B
Activin receptor type-2B isoform X1.
  
0.732
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.