close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATF6Activating transcription factor 6. (704 aa)    
Predicted Functional Partners:
MBTPS2
Membrane-bound transcription factor site-2 protease isoform X1.
     
 0.928
MBTPS1
Membrane-bound transcription factor site-1 protease isoform X1.
     
 0.924
HSPA5
Endoplasmic reticulum chaperone BiP.
    
 0.864
XBP1
LOW QUALITY PROTEIN: X-box-binding protein 1.
    
 0.834
CALR
Calreticulin.
     
 0.718
DDIT3
DNA damage inducible transcript 3.
   
 0.696
EIF2AK3
Eukaryotic translation initiation factor 2-alpha kinase 3.
    
 
 0.688
HSP90B1
Heat shock protein 90kDa beta.
     
 0.681
ATF4
Cyclic AMP-dependent transcription factor ATF-4.
      
 0.677
EIF2S1
Eukaryotic translation initiation factor 2 subunit 1.
      
 0.631
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.