close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LMAN1Protein ERGIC-53 isoform X1. (499 aa)    
Predicted Functional Partners:
MCFD2
Multiple coagulation factor deficiency protein 2 isoform X1.
   
 0.995
SEC22B
Vesicle-trafficking protein SEC22b isoform X1.
   
 0.831
TMED2
Transmembrane emp24 domain-containing protein 2 isoform X2.
   
 0.830
GOSR2
Golgi SNAP receptor complex member 2 isoform X1.
     
 0.815
SEC13
Protein transport protein SEC13.
   
 
 0.799
SEC24C
Protein transport protein Sec24C isoform X1.
   
 
 0.779
SEC23B
Protein transport protein Sec23B isoform X1.
   
 
 0.777
SEC23A
Protein transport protein Sec23A.
   
 
 0.777
TMED10
Transmembrane emp24 domain-containing protein 10.
   
 0.756
PREB
Prolactin regulatory element-binding protein isoform X1.
   
 0.755
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.