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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CPLX4Complexin-3/4. (160 aa)    
Predicted Functional Partners:
RAX2
Retina and anterior neural fold homeobox protein 2.
 
 
  
 0.546
RIMS2
Regulating synaptic membrane exocytosis 2.
      
 0.537
PHACTR1
Phosphatase and actin regulator 1.
      
 0.533
MAPK4
Mitogen-activated protein kinase 4/6.
    
 
 0.531
LMAN1
Protein ERGIC-53 isoform X1.
 
    
 0.509
DMXL2
DmX-like protein 2 isoform X1.
      
 0.509
SKA1
Spindle and kinetochore-associated protein 1.
      
 0.471
OTX2
Homeobox protein OTX2 isoform X1.
   
  
 0.465
ME2
Malic enzyme 2.
      
 0.446
KCNV2
Potassium voltage-gated channel subfamily V member 2.
   
  
 0.434
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.