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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBE2FUbiquitin-conjugating enzyme E2 F. (222 aa)    
Predicted Functional Partners:
LOC107199423
NEDD8-like.
   
 0.991
UBA3
NEDD8-activating enzyme E1 catalytic subunit isoform X1.
    
 0.981
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 0.981
NAE1
Amyloid beta precursor protein binding protein 1.
    
 0.974
CUL1
Cullin-1 isoform X1.
    
 0.963
UBE2V1
Ubiquitin-conjugating enzyme E2 variant 1.
    
 0.960
DCUN1D3
DCN1-like protein 3.
    
 0.953
RNF7
RING-box protein 2 isoform X1.
    
 0.952
BIRC6
Baculoviral IAP repeat-containing protein 6 isoform X1.
    
 0.941
UBXN7
UBX domain-containing protein 7.
   
 
 0.938
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.