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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NGFRTumor necrosis factor receptor superfamily member 16. (650 aa)    
Predicted Functional Partners:
NTF3
Neurotrophin-3 isoform X1.
    
 0.991
NGF
Nerve growth factor, beta.
     
  0.925
BDNF
Brain-derived neurotrophic factor isoform X1.
    
 0.901
LINGO1
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein.
    
 0.895
TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1.
    
 
 0.821
TRAF6
TNF receptor-associated factor 6.
    
 0.820
EFNA5
Ephrin-A5 isoform X1.
     
 0.788
OMG
Oligodendrocyte myelin glycoprotein.
    
 0.786
NTRK2
BDNF/NT-3 growth factors receptor isoform X1.
   
 0.786
LOC107209761
Receptor-interacting serine/threonine-protein kinase 2-like isoform X1.
    
  0.775
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.