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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDRG1P53 and DNA damage-regulated protein 1. (132 aa)    
Predicted Functional Partners:
RPAP3
RNA polymerase II-associated protein 3.
    
 
 0.771
PIH1D1
PIH1 domain-containing protein 1.
    
 
 0.736
WDR92
WD repeat-containing protein 92.
    
 
 0.710
POLR2E
DNA-directed RNA polymerases I, II, and III subunit RPABC1.
    
 
 0.672
URI1
Unconventional prefoldin RPB5 interactor 1.
    
 
 0.637
PFDN4
Prefoldin subunit 4.
    
 
 0.572
ARL14EP
ARL14 effector protein.
      
 0.533
SURF6
Surfeit 6.
      
 0.475
RUVBL1
RuvB-like protein 1 (pontin 52).
    
 
 0.433
SRP72
Signal recognition particle subunit SRP72.
      
 0.408
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.