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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC86Coiled-coil domain-containing protein 86. (225 aa)    
Predicted Functional Partners:
MRTO4
MRNA turnover protein 4 homolog.
   
   0.614
UFSP2
Ufm1-specific protease 2 isoform X1.
      
 0.533
NIP7
60S ribosome subunit biogenesis protein NIP7 homolog.
   
    0.517
TM2D1
TM2 domain containing 1.
      
 0.461
APTX
Aprataxin isoform X1.
      
 0.461
NHP2
H/ACA ribonucleoprotein complex subunit 2.
   
    0.454
LYAR
Cell growth-regulating nucleolar protein.
   
  
 0.441
GRWD1
Glutamate-rich WD repeat-containing protein 1.
   
    0.440
NSA2
Ribosome biogenesis protein NSA2 homolog.
   
   0.429
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.