close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EIF2AEukaryotic translation initiation factor 2A isoform X1. (619 aa)    
Predicted Functional Partners:
EIF3B
Eukaryotic translation initiation factor 3 subunit B.
   
 
0.922
EIF2AK4
Eukaryotic translation initiation factor 2-alpha kinase 4.
   
 
 0.670
EIF5B
Eukaryotic translation initiation factor 5B isoform X1.
   
  
 0.661
XRN1
5'-3' exoribonuclease 1.
    
 
 0.634
EIF2AK1
Eukaryotic translation initiation factor 2 alpha kinase 1.
   
 
 0.612
EIF2S1
Eukaryotic translation initiation factor 2 subunit 1.
   
 
 0.584
XBP1
LOW QUALITY PROTEIN: X-box-binding protein 1.
      
 0.567
EIF2S3
Eukaryotic translation initiation factor 2 subunit 3.
   
 
 0.532
COPS5
COP9 signalosome complex subunit 5.
    
 
 0.516
HARS1
Histidine--tRNA ligase, cytoplasmic-like isoform X1.
   
 
 0.503
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.