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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B2MBeta-2-microglobulin. (120 aa)    
Predicted Functional Partners:
WRN
Werner syndrome ATP-dependent helicase isoform X1.
   
 0.992
ENSPMJP00000004421
Class I histocompatibility antigen, F10 alpha chain-like.
   
 0.980
ENSPMJP00000005052
Class I histocompatibility antigen, F10 alpha chain.
   
 0.980
RPA1
Replication protein A 70 kDa DNA-binding subunit.
   
 0.971
RPA3
Replication protein A 14 kDa subunit.
   
 0.945
ENSPMJP00000004816
T-cell surface glycoprotein CD1b-3-like.
    
 0.941
RAD52
DNA repair protein RAD52 homolog isoform X1.
    
 0.936
ENSPMJP00000018528
annotation not available
   
 0.933
FANCM
Fanconi anemia group M protein.
   
 0.933
CD8A
T-cell surface glycoprotein CD8 alpha chain isoform X1.
   
 0.896
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.