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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPAG1Sperm-associated antigen 1. (969 aa)    
Predicted Functional Partners:
LEO1
RNA polymerase-associated protein LEO1 isoform X1.
    
 0.854
WDR92
WD repeat-containing protein 92.
    
 0.670
DNAAF5
Dynein assembly factor 5, axonemal.
      
 0.665
PIH1D1
PIH1 domain-containing protein 1.
    
 
 0.660
ZMYND10
Zinc finger MYND domain-containing protein 10 isoform X1.
   
 
 0.659
RUVBL2
RuvB-like protein 2.
    
 
 0.634
RUVBL1
RuvB-like protein 1 (pontin 52).
   
 0.602
BBS9
Bardet-Biedl syndrome 9 protein.
    
 0.583
DNAI2
Dynein intermediate chain 2, axonemal.
    
 0.577
RSPH1
Radial spoke head 1 homolog isoform X1.
    
 
 0.571
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.