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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDE5ACGMP-specific 3',5'-cyclic phosphodiesterase isoform X1. (973 aa)    
Predicted Functional Partners:
APRT
Adenine phosphoribosyltransferase.
     
 0.914
GMPR
GMP reductase 1 isoform X1.
    
 0.907
ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 isoform X2.
     
 0.905
ENPP3
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3.
     
 0.905
GUK1
Guanylate kinase isoform X1.
   
 
 0.904
GMPS
GMP synthase (glutamine-hydrolysing).
     
  0.900
HPRT1
Hypoxanthine-guanine phosphoribosyltransferase.
     
  0.900
GUCY1B1
Guanylate cyclase soluble subunit beta-1.
   
 0.814
LOC107208956
Guanylate cyclase soluble subunit beta-2-like isoform X1.
   
 0.814
PDE2A
CGMP-dependent 3',5'-cyclic phosphodiesterase isoform X1.
    
0.792
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.