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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARP6Poly [ADP-ribose] polymerase 6 isoform X1. (713 aa)    
Predicted Functional Partners:
RPL5
Large subunit ribosomal protein L5e.
  
 
 0.859
RPS15
Small subunit ribosomal protein S15e.
  
 0.854
RPL11
Large subunit ribosomal protein L11e.
  
 
 0.853
RPL23A
Large subunit ribosomal protein L23Ae.
  
 
 0.848
RPS3
Small subunit ribosomal protein S3e.
  
 
 0.832
RPS4X
40S ribosomal protein S4, X isoform.
  
   0.814
GPI
Glucose-6-phosphate isomerase.
  
 
 0.813
RPL23
Large subunit ribosomal protein L23e.
  
   0.811
RPL32
Large subunit ribosomal protein L32e.
  
   0.811
RPS11
Small subunit ribosomal protein S11e.
  
 
 0.810
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.