Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PARP6Poly [ADP-ribose] polymerase 6 isoform X1. (713 aa)    
Predicted Functional Partners:
PGK1
Phosphoglycerate kinase 1.
  
 0.855
ENSPMJP00000007082
annotation not available
  
 0.810
ENO2
Gamma-enolase.
  
 0.810
ENO1
Alpha-enolase isoform X1.
  
 0.810
TPI1
Triosephosphate isomerase (TIM).
  
 
 0.803
GPI
Glucose-6-phosphate isomerase.
  
 0.794
ENO4
Enolase 4.
  
 0.785
GAPDH
Glyceraldehyde 3-phosphate dehydrogenase.
  
 
 0.775
PGAM1
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase.
  
 0.770
BPGM
Bisphosphoglycerate/phosphoglycerate mutase.
  
 0.770
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
Server load: low (40%) [HD]