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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CATCatalase. (528 aa)    
Predicted Functional Partners:
SOD2
Superoxide dismutase [Mn], mitochondrial.
  
 0.956
SCP2
Non-specific lipid-transfer protein.
   
 0.951
HAO1
Hydroxyacid oxidase 1 isoform X1.
   
 
 0.942
SOD1
Superoxide dismutase 1.
  
 0.939
SOD3
Extracellular superoxide dismutase [Cu-Zn].
  
 0.939
KYNU
Kynureninase isoform X1.
   
 
 0.912
HAAO
3-hydroxyanthranilate 3,4-dioxygenase isoform X1.
   
 
  0.910
HSDL2
Hydroxysteroid dehydrogenase-like protein 2.
   
 0.906
HTD2
Hydroxyacyl-thioester dehydratase type 2.
   
 0.900
RGN
Gluconolactonase.
   
 
 0.869
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.