STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF5Rho guanine nucleotide exchange factor 5 isoform X1. (1737 aa)    
Predicted Functional Partners:
ROCK1
Rho-associated protein kinase 1 isoform X1.
    
 0.669
NEK11
NIMA (never in mitosis gene a)-related kinase 11.
      
 0.533
FAM72A
Protein FAM72A isoform X2.
      
 0.529
LOC107200563
TRPM8 channel-associated factor 2 isoform X1.
      
 0.520
CDC42
Cell division control protein 42 homolog isoform X1.
    
 0.494
ARHGAP11A
Rho GTPase-activating protein 11A isoform X1.
      
 0.452
NEPRO
Protein nepro homolog.
  
     0.422
RHOB
Rho-related GTP-binding protein RhoB.
    
 0.418
RHOA
Ras homolog gene family, member A.
    
 0.418
RHOC
Rho-related GTP-binding protein RhoC isoform X1.
    
 0.418
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.