STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASP8Uncharacterized protein LOC107207226. (480 aa)    
Predicted Functional Partners:
FADD
FAS-associated death domain protein.
   
0.940
RIPK1
Receptor-interacting serine/threonine-protein kinase 1 isoform X1.
   
 0.867
TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1.
    
 0.857
APAF1
Apoptotic protease-activating factor 1 isoform X1.
    
 0.835
CFLAR
CASP8 and FADD-like apoptosis regulator isoform X1.
   
0.821
FAS
Tumor necrosis factor receptor superfamily member 6.
   
 0.808
XIAP
E3 ubiquitin-protein ligase XIAP isoform X1.
   
 0.793
LOC107213952
LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 10B-like.
    
 0.741
CASP3
Caspase 3.
  
0.738
FASLG
Tumor necrosis factor ligand superfamily member 6.
   
 0.725
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.