STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIK95615.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)    
Predicted Functional Partners:
AIK96370.1
Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.905
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
   
 
  0.725
AIK95554.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.715
AIK95555.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.715
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
  0.703
AIK97038.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the heat shock protein 70 family.
   
  0.703
AIK95556.1
FAD-linked oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.662
AIK96236.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.605
AIK95637.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.577
AIK97014.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.541
Your Current Organism:
Paracaedibacter acanthamoebae
NCBI taxonomy Id: 91604
Other names: C. Paracaedibacter acanthamoebae, Candidatus Paracaedibacter acanthamoebae, endosymbiont of Acanthamoeba sp. UWC9
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