STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0C9LZZ5Sphingosine-1-phosphate phosphohydrolase. (442 aa)    
Predicted Functional Partners:
A0A0C9MMI3
PLP-dependent transferase.
    
 0.957
A0A0C9MLH4
Sphinganine C4-hydroxylase; Belongs to the sterol desaturase family.
    
 0.885
A0A0C9N3M1
Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.
    
 0.885
A0A0C9LYC2
Cyclin-dependent protein kinase inhibitor.
  
 0.859
A0A0C9M438
DUF4396 domain-containing protein.
    
 0.838
MED20
Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.838
A0A0C9MWB6
Glutamate decarboxylase; Belongs to the group II decarboxylase family.
    
 0.838
A0A0C9N166
Glutamate decarboxylase; Belongs to the group II decarboxylase family.
    
 0.838
A0A0C9MJZ5
Oxidoreductase.
    
 0.835
A0A0C9LZX0
Sphingosine kinase.
   
 0.832
Your Current Organism:
Mucor ambiguus
NCBI taxonomy Id: 91626
Other names: M. ambiguus
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.