node1 | node2 | node1 annotation | node2 annotation | score |
A0A0C9LR32 | A0A0C9LV32 | FACT complex component Spt16. | Histone H2A; Belongs to the histone H2A family. | 0.905 |
A0A0C9LR32 | A0A0C9M0H6 | FACT complex component Spt16. | DNA-directed RNA polymerase II polypeptide. | 0.973 |
A0A0C9LR32 | A0A0C9M3P8 | FACT complex component Spt16. | FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] | 0.999 |
A0A0C9LR32 | A0A0C9MC65 | FACT complex component Spt16. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.983 |
A0A0C9LR32 | A0A0C9ME97 | FACT complex component Spt16. | RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. | 0.573 |
A0A0C9LR32 | A0A0C9MJT5 | FACT complex component Spt16. | RPOLD domain-containing protein. | 0.985 |
A0A0C9LR32 | A0A0C9MUN5 | FACT complex component Spt16. | Uncharacterized protein. | 0.798 |
A0A0C9LV32 | A0A0C9LR32 | Histone H2A; Belongs to the histone H2A family. | FACT complex component Spt16. | 0.905 |
A0A0C9LV32 | A0A0C9M0H6 | Histone H2A; Belongs to the histone H2A family. | DNA-directed RNA polymerase II polypeptide. | 0.839 |
A0A0C9LV32 | A0A0C9M3P8 | Histone H2A; Belongs to the histone H2A family. | FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] | 0.685 |
A0A0C9LV32 | A0A0C9MC51 | Histone H2A; Belongs to the histone H2A family. | Serine/threonine-protein kinase. | 0.776 |
A0A0C9LV32 | A0A0C9MC65 | Histone H2A; Belongs to the histone H2A family. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.997 |
A0A0C9LV32 | A0A0C9ME97 | Histone H2A; Belongs to the histone H2A family. | RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. | 0.977 |
A0A0C9LV32 | A0A0C9MJT5 | Histone H2A; Belongs to the histone H2A family. | RPOLD domain-containing protein. | 0.908 |
A0A0C9LV32 | A0A0C9MUN5 | Histone H2A; Belongs to the histone H2A family. | Uncharacterized protein. | 0.787 |
A0A0C9M0H6 | A0A0C9LR32 | DNA-directed RNA polymerase II polypeptide. | FACT complex component Spt16. | 0.973 |
A0A0C9M0H6 | A0A0C9LV32 | DNA-directed RNA polymerase II polypeptide. | Histone H2A; Belongs to the histone H2A family. | 0.839 |
A0A0C9M0H6 | A0A0C9M3P8 | DNA-directed RNA polymerase II polypeptide. | FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] | 0.971 |
A0A0C9M0H6 | A0A0C9MC65 | DNA-directed RNA polymerase II polypeptide. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.966 |
A0A0C9M0H6 | A0A0C9MJT5 | DNA-directed RNA polymerase II polypeptide. | RPOLD domain-containing protein. | 0.999 |